MaitakeGold® & Capros®

Key Points:

  1. Increased levels of immune-enhancing cytokines, including IL-2 and IFN-gamma (MaitakeGold®)
  2. Increased levels of anti-inflammatory cytokines, including, IL-10 (MaitakeGold®)
  3. Enhanced cytokine producing T-cell activity (MaitakeGold®)
  4. Superior antioxidant activity (Capros®)

 

 

Capros® is a standardized natural extract of the ultimate superfruit antioxidant “beauty food”, Indian Gooseberry (Phyllanthus emblica) and is offered exclusively by Nutramins. Carpos® is a super antioxidant (ORACFN of 47,000 µmoles TE/g), due to it high content of hydrolysable tannins polyphenols.

 

MaitakeGold® is simply the best Maitake extract in the world. In 1984, Dr. Hiroaki Nanba of Kobe Pharmaceutical University (Kobe, Japan) began work with his team on the development of an orally effective, immune enhancing extract derived from Maitake (Grifola frondosa) mushroom. This led to a critical discovery in the late 1990’s when they found inherent in the Maitake extract a substance or “float” that inhibits the immune enhancing properties of the extract. The Nanba team went on to develop a proprietary process to eliminate this substance from the extract, for which Dr. Nanba  was awarded a United States patent (5,854,404). Dr. Nanba has stated this proprietary extract is the most therapeutically concentrated Maitake extract available to date and is marketed exclusively under the tradename, MaitakeGold®. The patent states:

“The main feature is to enhance the immunopotentiating activity by removing floating or adhering matter. Because the removal of the floating and adhering matter brings about enhancement in the immunopotentiating activity of the extract, the step of removing said matter is extremely important.”

 

Years of rigorous scientific research at some of the world’s most prestigious institutions has shown that MaitakeGold® is one of the most therapeutically bioactive Maitake extracts yet developed for enhanced immune support, even at relatively small doses. Researchers at Memorial Sloan Kettering Research Hospital found that MaitakeGold® enhanced several indicators of healthy immune function in a multi-phase, U.S. Government funded human clinical trial. The results provided evidence that MaitakeGold® significantly enhanced immune support when taken orally. In particular, these studies showed that MaitakeGold® helps enhance a variety of immune cell components and cytokines at low dosages.

 

MaitakeGold® is derived from a strain of Maitake mushroom fruit body that is cultivated using proprietary techniques. It is then extracted using a proprietary hydro-alcoholic process that was granted a U.S. patent in 1998, creating one of the most comprehensive immunomodulators available in the dietary supplement category.

 

 

Summary of MaitakeGold® Clinical Trial:

 

A three year,  U.S. Government-funded, multi-phase, human clinical study of  MaitakeGold’s immune-enhancing properties was conducted at Memorial Sloan-Kettering Hospital, one of the world’s foremost medical research facilities. In a Phase I/II trial, 34 subjects took MaitakeGold® at varying doses for three weeks. Researchers discovered that balanced immune support (immunomodulation) occurred in subjects at all dosage levels (including low doses), with no adverse effects. After three weeks, T cell activity increased, as did levels of immune-enhancing cytokines (IL-2, TNF-alpha, IFN-gamma), and other cytokines (IL-10). This study demonstrated that MaitakeGold® helps support healthy immune function.

These results, together with animal and ex-vivo studies conducted at the University of Louisville, demonstrate that MaitakeGold® is highly efficacious and bioavailable when taken orally and is appropriate for extended daily use, unlike some other natural immune products such as Echinacea which should be taken for short periods only.

 

Deng, G, et al. 2009. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: Immunological effects. J. Cancer Res. Clin. Oncol. 135:1215-1221.

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